Marland Lab

Bioelectronics & Microsystems Engineering

We are an interdisciplinary research group, working at the interface between electronics and biology. We develop miniature devices that sense biological signals directly from living systems, focusing particularly on synthetic biology and human physiology applications.

Recent examples of our work include implantable sensors for real-time health monitoring, electrodes that read outputs from engineered cell-free systems, and ultra-thin nanowires capable of sensing the electric fields of individual biomolecules.

Underpinning this research are tools and techniques from the semiconductor industry. These enable us to nanofabricate bioelectronic systems that bridge the size gap between biological molecules and engineered devices. This approach facilitates highly reproducible and scalable manufacturing, and offers a pathway for future translation.

Our team is based in the Institute for Integrated Micro and Nano Systems at the University of Edinburgh, and is also a member of the Centre for Engineering Biology and the Institute for Bioengineering. We closely engage with end-users to ensure our research has maximum value and impact, and collaborate across the University and NHS Lothian.

news

Aug 10, 2026 Our new paper, “Horseradish peroxidase as an electrochemical reporter protein for cell-free biosensors”, has been published in Synthetic Biology. The study was led by PhD student Aarushi Ruhela, working with our collaborator Dr Nadanai Laohakunakorn, and shows that cell-free-expressed horseradish peroxidase can provide an electrochemical output as an alternative to optical reporters for future portable biosensors.
Aug 04, 2026 Great to attend IEEE BioSensors 2026 in Bangkok, Thailand, where we presented a poster on “Aptamer Functionalised Silicon Nanowire Field-Effect Transistors for Selective Dopamine Detection”. It was an excellent opportunity to hear how the field is moving beyond ever-lower detection limits towards continuous, multiplexed biosensors designed for real-world translation.
Jul 07, 2026 Jamie Marland has been awarded Fellowship of the Higher Education Academy (FHEA), recognising his teaching and support for learning in higher education.
Jun 29, 2026 This summer Keshavi Nalla attended the Una Europa Summer School 2026 at Università di Bologna, exploring the principles, properties, and applications of soft materials, from molecular systems to biomaterials.
Jun 16, 2026 Many congratulations to Jennifer Dong on passing her PhD viva for her thesis, “Silicon Nanowire Field-Effect Transistor Biosensors Fabricated Using Thermal Scanning Probe Lithography” - well done Dr Dong!